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No PCT needed surely...?! - 05-06-2008

Just finishing an anavar only cycle. due to the nature of anavar surely i won't "shut down" so surely i wont need a PCT...I have loadsa nolva on hand if needs be. Maybe just some 6-oxo and tribulus maybe??
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murrellm's Avatar
Member
 
05-07-2008

Hey bro, most people claim that Anavar won't shut down the HPTA completely but that is only at low dosages. To be on the safe side I would do at least 2 weeks of a PCT.


Below is a medical study on that Anavar suppression at low dosages.


Effect of low dose oxandrolone and testosterone treatment on the pituitary-testicular and GH axes in boys with constitutional delay of growth and puberty.

Crowne EC, Wallace WH, Moore C, Mitchell R, Robertson WH, Holly JM, Shalet SM.

Department of Endocrinology, Christie Hospital Trust, Manchester, UK.

OBJECTIVE: To investigate the effect of low dose oxandrolone and testosterone on the pituitary-testicular and GH-IGF-I axes. DESIGN: Prospective double-blind placebo-controlled trial. PATIENTS: Sixteen boys with constitutional delay of growth and puberty (CDGP) with testicular volumes 4-6 ml were randomized to 3 months treatment: Group 1 (n = 5), daily placebo: Group 2 (n = 5), 2.5 mg oxandrolone daily or Group 3 (n = 6), 50 mg testosterone monthly intramuscular injections with assessment (growth, pubertal development and overnight hormone profiles) at 0, 3, 6 and 12 months. MAIN OUTCOME MEASURES: LH and GH profiles (15-minute samples) were analysed by peak detection (Pulsar), Fourier transformation and autocorrelation. Testosterone levels were measured hourly and insulin, SHBG, IGF-I, and IGFBP-3 levels at 0800 h. Statistical analysis was by multivariate analysis of variance for repeated measures. RESULTS: LH and testosterone parameters increased significantly with time in all 16 (LH AUC, P < 0.001; peak amplitude, P = 0.02; number of peaks, P = 0.02; testosterone AUC, P = 0.02; morning testosterone, P = 0.002). In Group 2, however, LH and testosterone parameters decreased at 3 months followed by a rebound increase at 6 and 12 months. SHBG levels were markedly reduced at 3 months (P = 0.006) and a wider range of dominant GH frequencies was present although GH AUC was not increased until 6 months, with an increase in GH pulse frequency but not amplitude. IGF-I levels were increased at both 3 and 12 months. In Group 3, pituitary-testicular suppression was not apparent, but GH levels increased with an increase in GH amplitude at 3 and 12 months. CONCLUSION: Oxandrolone transiently suppressed the pituitary-testicular axis and altered GH pulsatility. Testosterone increased GH via amplitude modulation.
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fla2tn's Avatar
Senior Member
 
05-07-2008

Agreed...........especially if ya have tons on hand what could it hurt bro?


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Member
 
05-07-2008

alright, probs best to be safe.cheers
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jamoliv's Avatar
Moderator
 
05-07-2008

aahh the great debate on var and the HPTA - some say it does have an impact some say it does not.. we are all different when it comes to AAS-

if your not sure just run a pct - it wont do any harm
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REX's Avatar
REX REX is offline
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05-07-2008

Quote:
Originally Posted by jamoliv View Post
aahh the great debate on var and the HPTA - some say it does have an impact some say it does not.. we are all different when it comes to AAS-

if your not sure just run a pct - it wont do any harm
bump, some sort of PCT is always a good idea for any cycle with AAS

Rex


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Duration Dosage FOR CLOMID
Day 1 300mg
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