Tamoxiplex (Tamoxifen Citrate) is a drug referred to as an anti-estrogen. Actually, Tamoxiplex is an estrogen antagonist, meaning it competes with estrogen at estrogen receptor- sites. This prevents the active estrogen from entering its receptor and creating an estrogenic complex capable of activity. Since many AAS aromatize (convert to estrogen) to some degree, the control of feminizing side effects (males should pay attention here) is important. Males normally have a very low estrogen level. During AAS cycles, due to aromatization, estrogen levels rise considerably. This elevated estrogen level can cause feminizing side effects such as increased fat deposits, water retention, and gynecomastia (growth of breast gland tissue and painful tumors under the nipple). As a rule, it is more the ratio of androgens to estrogens than the simple increase in estrogen that actually initiates feminizing side effects.
It is important that the reader realizes that Tamoxiplex does not decrease estrogen production and that it simply blocks estrogen receptors. For this reason the sudden discontinuance of Tamoxiplex will allow the increased level of circulating estrogen to merge with the newly freed receptors and do feminine things to the body.

Tamoxiplex is very comparable to Clomiplex (Clomiphene Citrate), behaves in the same manner in all tissues, and is a mixed estrogen agonist/antagonist of the same type as Clomiplex (Clomiphene Citrate). The two molecules are also very similar in structure. While practically similar compounds in structure, few people ever really consider Clomiplex (Clomiphene Citrate) and Tamoxiplex (Tamoxifen Citrate) to be similar. Its not just a common myth in steroid circles, but even in the medical community. This misconception originates from their completely different uses. Tamoxiplex (Tamoxifen Citrate) is most commonly used for the treatment of breast cancer in women, while Clomiplex (Clomiphene Citrate) is generally considered a fertility aid. In bodybuilding circles, from day one, Clomiplex (Clomiphene Citrate) has generally been used as post-cycle therapy and Tamoxiplex (Tamoxifen Citrate) as an anti-estrogen.

The claim that Tamoxiplex (Tamoxifen Citrate) reduces gains should not be taken too seriously. The fact is that any number of bodybuilders have made excellent gains while using Tamoxiplex (Tamoxifen Citrate). The belief that it reduces gains seems to stem from the fact that the scientific literature reports a slight reduction in IGF-1 (individuals using anabolic steroids were not studied though) from use of Tamoxiplex (Tamoxifen Citrate). However, the effect of gains reduction exists at all, it must be very minor, due to the excellent gains that many have made, and from the fact that no one has noticed any such thing from Clomiplex, which has the same activity profile.

Several bodybuilders like to use Tamoxiplex (Tamoxifen Citrate) at the end of a steroid cycle since it increases the body's own testosterone production which will be discussed in more detail in the following-to counter-act the side effects caused by the estrogens. These can occur after the discontinuance of steroids when the androgen level in relationship to the estrogen concentration is too low and estrogen becomes the dominant hormone. A very rare but all the more serious problem of Tamoxiplex (Tamoxifen Citrate) is that in some cases it does not lower the estrogen level but can increase it. Another disadvantage is that it can weaken the anabolic effect of some steroids. The reason is that Tamoxiplex (Tamoxifen Citrate), as we know, reduces the estrogen level. The fact is, however, that certain steroids especially the various testosterone compounds can only achieve their full effect if the estrogen level is sufficiently high. Those who are used to the intake of larger amounts of various steroids do not have to worry about this. Athletes however, who predominantly use mild steroids such as Primoplex 100 (Methenolone Enanthate), Stanaplex 50 (Stanozolol), Oxandroplex (Oxandrolone) and Decaplex (Nandrolone Decanoate) should carefully consider whether or not they should take Tamoxiplex (Tamoxifen Citrate) since, due to the compound's already moderate anabolic effect, an additional loss of effect could take place, leading to unsatisfying results.

HOW DOES IT WORK:

The normal application of Tamoxiplex (Tamoxifen Citrate) is in the treatment of certain forms of breast cancer in female patients. With Tamoxiplex (Tamoxifen Citrate) it is possible to reverse an existing growth process of deceased tissue and prevent further growth. The growth of certain tissues is stimulated by the body's own estrogen hormone. This is especially true for the breast glands in men and women since the body has a large number of estrogen receptors at these glands which can bond with the estrogens present in the blood. If the body's own estrogen level is unusually high an undesired growth of breast glands occurs. However, in healthy women and particularly in men this is not the case. Despite this, it is mostly male bodybuilders who use Tamoxiplex (Tamoxifen Citrate), and fewer women. At first sight this seems somewhat inconceivable but when taking a closer look, the reasons are clear.

Bodybuilders who take Tamoxiplex (Tamoxifen Citrate) also use at the same time anabolic steroids. Since most steroids aromatize more or less strongly, that is to say part of the substance is converted into estrogens, male bodybuilders can experience a significant elevation in the normally very low estrogen level. This can lead to feminization symptoms such as gynecomastia (growth of breast glands), increased fat deposits and higher water retention.

Tamoxiplex (Tamoxifen Citrate) acts against this by blocking the estrogen receptors of the affected body tissue, thereby inhibiting a bonding of estrogens and receptor. It is, however, important to understand that Tamoxiplex does not prevent the aromatization but only acts as an estrogen antagonist. This means that it does not prevent testosterone and its synthetic derivatives (steroids) from converting into estrogens but only fights with them in a sort of "competition" for the estrogen receptors. This characteristic has the disadvantage that after the discontinuance of Tamoxiplex a "rebound effect" can occur which means that the suddenly freed estrogen receptors are now able to absorb the estrogen present in the blood. For this reason the combined intake of Proviraplex (Mesterolone) is suggested (see Proviraplex (Mesterolone).)
Tamoxiplex is also useful during a diet since it helps in the burning of fat. Although Tamoxiplex has no direct fatburning effect its anti-estrogenic effect contributes to keeping the estrogen level as low as possible. Tamoxiplex should especially be taken together with the strong androgenic steroids Methanoplex (Methandienone) and Oxyplex (Oxymetholone), and the various testosterone compounds. Athletes who have a tendency to retain water and who have a mammary dysfunction should take Tamoxiplex as a prevention during every steroid cycle. Since Tamoxiplex is very affective in most cases it is no wonder that several athletes can take Oxyplex (Oxymetholone) and Methanoplex (Methandienone) until the day of a competition, and in combination with a diuretic still appear totally ripped in the limelight. Those who already have a low body fat content will achieve a visibly improved muscle hardness with Tamoxiplex.

SIDE EFFECTS:

The side effects of Tamoxiplex are usually low in dosages of up to 30 mg/day. In rare cases nausea, vomiting, hot flashes, numbness, and blurred vision can occur. In women irregular menstrual cycles can occur which manifest themselves in weaker menstrual bleeding or even complete missing of a period. Women should also be careful not to get pregnant while taking Tamoxiplex. It is important for female athletes that Tamoxiplex and the "pill" not be taken together since the antiestrogen Tamoxiplex and the estrogen-containing pill negatively counterfeit each other.