I have been taking lipodrene with ephedra and it has lost its effectivness is clen a good alternative for weight loss i am looking to shed 15 lbs also is it safe I have epilepsy and have never had problems with ephedra will clen be as safe Best Regards

How old are you?
Are you working-out or keeping to a diet?

I am 38 and do cardio 6 days a week- pilates 2 days/ circuit 2 days and I stay on a fairly strict diet but my down fall is always evenings so I thought clen could be a good addition Thanks for responding

How long should you wait to take clen after taking ephedra?

Higher doses of clenbuterol may affect tissue excitability; such an effect may occur especially in conditions of hyperexcitability owing to use-dependent block of sodium channels. Interestingly, such a mechanism of action was recently proposed for the beneficial effect of clenbuterol in various seizure models of experimental epilepsy (Fischer et al., 2001).
At the skeletal muscle level, sarcolemmal hyperexcitability leads to myotonia, a condition of muscle stiffness shared by various genetic muscle diseases (Cannon, 2001; Moxley, 2000; Meola, 2002).
On the basis of our results, it would be important to verify the therapeutic potential of clenbuterol in the myotonic syndromes. In particular, because of the possibility of combining antimyotonic activity with its well known anabolic action, clenbuterol might be remarkably indicated in the treatment of myotonic dystrophy, the most common hereditary disease of skeletal muscle, characterized by muscle wasting together with permanent or fluctuans myotonia (Meola, 2002).
On the other hand, because sodium channel block may accentuate paralysis, clenbuterol should not be administrated to patients with HPP, whereas other 2-agonists, such as salbutamol, have proven to be beneficial in those patients, most probably because 2-adrenoceptor stimulation activates the Na,K-ATPase and consequently hyperpolarizes the muscle fiber (Wang and Clausen, 1976; Clausen et al., 1993; Hanna et al., 1998).

Caution is advised when employing the use of Clenbuterol in conjunction with other adrenoceptor agonists as side effects are likely to be cumulative. It is for this reason that it is generally not recommended to use ephedrine/ephedra (or ma huang) or the ECA stack (ephedrine-caffeine-aspirin) whilst using clenbuterol.
In view of the above side effects, it is obvious to assume that anyone with cardiac issues and/or hypertension should not use a stimulant such as Clenbuterol and caution must be observed by those already using similar compounds in the treatment of existing medical conditions.

Wait for 1 week.

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