Great info Kev, I'm in my mid forties and have a few cycles behind me too.
I take a few supplements to help combat the negative sides. NOW makes a good prostate support supplement and I also take their Liver detoxifier. I test my liver and kidney functions once and awhile and so far I'm seeing good results. I'd say go easy on the orals,
stay under 6 weeks,don't go crazy with the mg's and you should be fine. Test E is hard to beat in my opinion.
Good luck, and keep training